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KMID : 0545120180280030397
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Journal of Microbiology and Biotechnology
2018 Volume.28 No. 3 p.397 ~ p.400
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Anti-Obesity Effect of Red Radish Coral Sprout Extract by Inhibited Triglyceride Accumulation in a Microbial Evaluation System and in High-Fat Diet-Induced Obese Mice
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Lee Nam-Keun
Cheon Chun-Jin
Rhee Jin-Kyu
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Abstract
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Rhodosporidium toruloides, an oleaginous yeast, can be used as a fast and reliable evaluation tool to screen new natural lipid-lowering agents. Herein, we showed that triglyceride (TG) accumulation was inhibited by 42.6% in 0.1% red radish coral sprout extract (RRSE)-treated R. toruloides. We also evaluated the anti-obesity effect of the RRSE in a mouse model. The body weight gain of mice fed a high-fat diet (HFD) with 0.1% RRSE (HFD-RRSE) was significantly decreased by 60% compared with that mice fed the HFD alone after the 8-week experimental period. Body fat of the HFD-RRSE-fed group was dramatically reduced by 38.3% compared with that of the HFD-fed group.
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KEYWORD
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Rhodosporidium toruloides, red radish coral sprout, triglyceride, anti-obesity
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